Monoclonal Antibodies: A New Era in Multiple Sclerosis Treatment and The Future of Developing New Technique for Treat Neurological Disorders.

Saif sultan Alsahli, Awid mshain Almutiry, Obaid faris Aldossari.

Abstract

Multiple sclerosis (MS) is a chronic, inflammatory disorder of the CNS characterized by demyelination and neurodegeneration of the brain, spinal cord, and optic nerve. It frequently results in cognitive and physical disability.

The Diverse Applications of Cladistic Analysis of Molecular Evolution, with Special Reference to Nested Clade Analysis.

Alan R. Templeton

Abstract

The genetic variation found in small regions of the genomes of many species can be arranged into haplotype trees that reflect the evolutionary genealogy of the DNA lineages found in that region and the accumulation of mutations on those lineages.

Neuroprotective Effects of Ischemic Preconditioning on Global Brain Ischemia through Up-Regulation of Acid-Sensing Ion Channel 2a.

Yifeng Miao,Weiqiao Zhang,Yuchang Lin,Xiaojie Lu, Yongming Qiu.

Abstract

Transient forebrain or global ischemia induces cell death in vulnerable CA1 pyramidal neurons. A brief period of ischemia, i.e., ischemic preconditioning, affords CA1 neurons robust protection against a subsequent, more prolonged ischemic challenge.

Effective Population Size, Gene Flow, and Species Status in a Narrow Endemic Sunflower, Helianthus neglectus, Compared to Its Widespread Sister Species, H. petiolaris.

Andrew R. Raduski,Loren H. Rieseberg, Jared L. Strasburg.

Abstract

Species delimitation has long been a difficult and controversial process, and different operational criteria often lead to different results. In particular, investigators using phenotypic vs. molecular data to delineate species may recognize different boundaries.

In Vivo Study of the Effects of Peptide-Conjugated Near-Infrared Fluorescent Quantum Dots on the Tumorigenic and Lymphatic Metastatic Capacities of Squamous Cell.

Zhi-Gang Li,Kai Yang,Yu-An Cao,Gang Zheng,De-Ping Sun,Cheng Zhao, Jia Yang.

Abstract

Quantum dots (QDs) have great potential in non-invasive monitoring and imaging of tumor cells in vivo, but it is unknown if QDs affect their tumorigenesis and metastasis. Here, we applied peptide-conjugated near-infrared fluorescent QDs (NIRF-QDs).